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Notes on Attendance to the Sunbird Animal Industry Resistance Conference (April 23)

2019/02/27 18:23
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Dr. Cao Hong, Chief Scientist of New Hope VI: Food Safety and Transition

China's aquaculture industry is facing a series of serious problems, such as price fluctuation, uncontrollable market, high disease pressure, operational efficiency, asymmetric industry information, design of production safety system, management and operation mode, human resources allocation, aging equipment and so on. Food safety should be based on the basic concepts of non-toxic, non-residual, non-bacterial contamination and non-metabolic toxins. So what to do without anti-biotic breeding is not enough, only antibiotic substitutes, comprehensive stress management program should be considered.

High protein diet affects the growth and nutritional utilization of weaned piglets: high amino acid and low protein diet is the diet needed by piglets and chickens, all high protein diets can not digest piglets, when there are nutrients not absorbed in the intestin***

When problems arise in primary and secondary defenses, inflammation will occur.

Dr.Kim, North Carolina State University, USA: application of probiotics in non pig production


Two microecological agents can activate immune response; 2 DFM can interact with intestinal microorganisms, intestinal epithelial cells and immune cells to produce strong immune response; 3 In vivo and in vitro studies show that Lactobacillus and Bifidobacterium can stimulate macrophages, cytokine secretion, lymphocyte and enhance natural killing capacity;

The three microbial ecological agents can be either single-strain microorganisms or complex-strain microorganisms. The study found that the effects of different kinds of probiotics on the intestinal health, system health, growth performance and physical score of pigs under normal or infection stress conditions.

Experiment 1: 144 breeding pigs were selected, and the antibacterial growth promoters in feed were replaced by microecological preparations based on Lactobacillus acidophilus (2.4*109cfu/kg feed). The tester was 35 days. The results showed that Lactobacillus acidophilus with single strain had no beneficial effect on growth performance, fecal score, digesta count, pH value of digesta, cytokine and oxidative stress state of pigs.

Experiment 2: 20 conservation pigs were fed with microecological preparations based on Lactobacillus plantarum and Lactobacillus spp. (2.4*106cfu of each kg feed respectively) for 15 days. Microecological preparations containing two strains could improve the structure of villi, but had no effect on growth performance and nutrient digestibility.

Experiment 3: 32 selected pigs were fed with compound microecological preparation based on Lactobacillus acidophilus, Lactobacillus casei, Enterococcus faecium and Bifidobacterium (5*107cfu per kg feed additive), and F18+ oral enterotoxigenic Escherichia coli was infected. Despite being infected by ETEC, compound microecologic agents can increase body weight gain by increasing pig feed intake. In addition, probiotics can prevent damage to intestinal health caused by ETEC infection. Thus, the beneficial effect of compound microecological preparation on pig intestinal health is obvious.

Experiment 4: 60 growth finishing pigs were fed with microecological preparations based on Lactobacillus acidophilus (2.4*109cfu/kg feed) for 10 weeks until they reached the listing weight to obtain growth performance and carcass index, including HCW, CCW, back fat thickness (first, tenth and last rib), lumbar muscle weight, lumbar muscle color, lumbar muscle marble score, drip loss and so on.

Experiment 5: 60 fattening pigs were selected to feed the compound microecologic preparations in Experiment 3 for 4 weeks to obtain growth performance and carcass index.

Conclusion: Compound microecologic preparation can improve the feed intake and body weight gain of pigs, but also improve carcass weight and lumbar muscle weight without affecting back fat thickness and lumbar muscle composition. The use of probiotics can promote the growth of pigs and improve the formation of lean meat by improving intestinal health and intake. Therefore, if we carefully select those strains that can be set in the small intestine and large intestine, then the use of probiotics will be an effective way to improve the intestinal health and growth performance of pigs. However, the single microorganism preparation has some limitations on improving the efficiency of intestinal health.

Dr. Erik Vanderbeke, Aveve Group, Belgium: Design Ideas and Applications of Non-Resistant Feed

A healthy intestine is the result of the interaction of the following factors: 1. composition of feed materials and nutrients; 2. composition of intestinal microorganisms; 3. selective inhibition of pathogenic microorganisms; 4. balance between intestinal microflora and pathogenic bacteria and immune system; 5. immune tolerance to bacteria and feed nutrients; 6. structure and integrity of digestive tract;

The microbial composition of the second intestine: 1. It is related to the age of animals; 2. The "maximum" microbial species = intestinal flora - normal balance state; 3. There are different microbial composition and quantity in different parts of the digestive tract;

The following causes can cause changes and migration of intestinal microorganisms: feed composition, nutrients, fiber composition, additives; pathogenic microorganisms invasion and pathogenic pressure; antibiotics for treatment; stress factors, etc.

Three solutions: the new nutritional balance theory 1 reduces the total protein level and the ratio of undigested protein to fermentable protein in hindgut; 2. the new feeding strategy is adopted to focus on the intake of young animals and multi-stage feeding.